What Is Delta 8 Half-Life?
Delta 8-THC, 11OH-delta 8-THC, and 11-oxo-delta 8THC with biological half-lives varied from 32 minutes to 12 and 6 minutes for the slower episodes. The brain cleared 11-OH- and 11oxo-delta 8THC more quickly than delta 8-THC. At 0.5 minutes after the Intravenous injection (10 mg/kg), the peak levels of 11-OHand 11-oxo 8-THC in the nervous system were higher (10.64 and 4.25 micrograms per gram, respectively) than delta 8THC (3.48 micrograms per gram). Relevant Points · This study found that 11-OH- and 11oxo-delta 8-THC can be conveyed from the brain to the blood system in rats faster than delta 8-THC. Something may explain why these metabolites have more substantial pharmacological effects than previously thought. · It was surprising to discover that 15 minutes after the injection of 11oxo-delta 8 THC (10 microgram/kg, IV), the brain had a greater amount of 11-OH delta 8-THC (3.27 microgram/g) than the liver (0.74 microgram/g) or the blood (0.29 microgram/ml).